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    • Home
    • Diagnostics
      • Polycythemia Vera
      • Essential Thrombocythemia
      • Primary Myelofibrosis
      • Congenital Erythrocytosis
      • Hereditary Thrombocytosis
    • Molecular analyses
      • JAK2V617F
      • JAK2 Exon 12 mutations
      • Mpl/TPO_Receptor
      • Calreticulin (CALR)
      • Other genes mutated in MPN
      • EPO-Receptor
      • Oxygen sensing pathway genes
      • THPO
    • Events
    • Useful links
    • Members
    • Registration
    • INTRANET

      Ljubljana April 22-24, 2020, Slovenia

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      • Ljubljana April 22-24, 2020, Slovenia

      Diagnosis and therapy of sporadic and hereditary myeloproliferative diseases

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      • Programme
      • Participants
      • Organization
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      COVID-19 Update

      Due to the Covid-19 epidemy, we have to postpone the Ljubljana meeting to the period between September – November. New meeting dates, programme and registration deadline will be known by the end of May. Please do follow our homepage for more information.

      MPN&MPNr Ljubljana organising committee

      Aims

      The aims of MPN&MPNr-EuroNet’s fifteenth meeting to be held in Ljubljana, Slovenia, on April 22-24 2020 are:

      1. to share information on the newest developments in MPNs and related congenital diseases, hereditary erythrocytosis and hereditary thrombocytosis;
      2. to exchange and diffuse the latest information and recommendations on the molecular assays developed for diagnosis or research in laboratories working on MPNs and related diseases across Europe. NGS and novel technologies will be special focuses of this meeting;
      3. to provide recommendations for therapy of MPN;
      4. to discuss and plan for the various tasks and objectives of the three MPN&MPNr-EuroNet working groups (WG);
      5. to help and mentor young scientists interested in MPNs and related congenital
        diseases, hereditary erythrocytosis and hereditary thrombocytosis.
        To do so, abstracts will be selected for short talks in the different sessions. Posters will
        be presented during the whole length of the meeting.
        Plenary sessions will cover the newest knowledge in MPNs, hereditary erythrocytosis and thrombocytosis. Each WG will convene under the direction of the WG chairs. New participants are encouraged to become actively involved in specific WG tasks.

      Objectives

      Participants to the fifteenth MPN&MPNr-EuroNet meeting will have the opportunity to hear from international experts about the newest developments in the molecular diagnosis of MPNs and related congenital/hereditary diseases. They will have the opportunity to present their own work and original diagnostic assays, and exchange with colleagues and experts on the newest genes and techniques of interest in the field of MPNs, congenital erythrocytosis and hereditary thrombocytosis. By joining one or more of MPN&MPNr-EuroNet working groups, they will be able to contribute actively, productively and durably in innovation, optimization and standardization of the biological diagnosis of MPNs and related congenital diseases in Europe.

      Keywords

      molecular diagnosis, myeloproliferative neoplasms, congenital erythrocytosis, hereditary thrombocytosis, standardization, European network

      More info

      Click on the following link to get more info about MPN&MPNr-EuroNet.

      Abstract Submission

      Participants are encouraged to submit an abstract in relation to the diagnosis of MPNs, hereditary erythrocytosis and thrombocytosis, new mutations and gene editing in MPNs, hereditary erythrocytosis and thrombocytosis, the histopathology, pathogenesis and inflammation in MPNs, the JAK/STAT and other signaling pathways and the mechanism of oxygen sensing. NGS and novel technologies will be the special focuses of this meeting.. Early stage researchers and junior biologists and clinicians are especially encouraged to submit abstracts.
      Abstracts should be composed as follows:

      • Title
      • Names of co-authors
      • Affiliations
      • E-mail address of corresponding author
      • Text (maximum 2000 characters, including spaces).

      All abstracts will be assembled in an abstract book that will be distributed to participants during the meeting.
      The deadline for submission of abstracts is March 2nd, 2020.

      In order to submit an abstract, participants should first be registered, then, being logged in, choose Abstract in the menu bar on Registration page.

      Programme

      PROGRAMME

      Diagnosis and therapy of sporadic and hereditary myeloproliferative diseases
      MPN&MPNr-EuroNet Fifteenth Meeting
      April 22-24, 2020
      Ljubljana, Slovenia

       

      Diagnosis and
      therapy of sporadic and hereditary myeloproliferative diseases

      MPN&MPNr-EuroNet Fifteenth Meeting

      April
      22-24, 2020

      Ljubljana, Slovenia

       

      PROGRAMME

       

      WEDNESDAY

      April 22nd, 2020

       

      13:00 – 13:45

      Registration

       

      13:45 – 14:00

      Welcome and Schedule

      Sylvie Hermouet (FR), Nataša Debeljak (SI), Irena Preložnik Zupan (SI)

       

       

       

      14:00-18:30

      Special Session I: Treatment of MPNs

      Special Session I is
      sponsored by Novartis.

      Co-chairs: Konstanze
      Döhner (DE),

      Matjaž Sever (SI)

      14:00-15:00

      Stem Cell Transplantation
      in MPNs

      Nicolaus Kröger
      (DE)

      15:00-16:00

      Early-stage Myelofibrosis

      Francesca
      Palandri (IT)

       

       

       

      16:00-16:30

      Coffee/tea break

      UMC

       

       

       

      16:30-17:30

      How I treat Polycythemia vera: Clinical practice

      Konstanze Döhner
      (DE)

      17:30-18:00

      Managing anaemia in Myelofibrosis

      Matjaž Sever (SI)

      18:00-18:20

      Which scoring system
      to use in Myelofibrosis

      Polona Novak (SI)

      18:20-18:30

      Discussion

       

       

       

       

      18:30

      Welcome Dinner

      UMC

       

       

       

      THURSDAY

      April 23rd, 2020

       

      8:15-9:45

      Special Session II: Clinical aspects of MPNs

      Co-chairs: Francesca
      Palandri (IT),
      Polona Novak (SI)

      8:15-9:00

      Ruxolitinib in Myelofibrosis:
      Clinical practice

      Francesca
      Palandri (IT)

      9:00-9:20

      Role of morphology
      in the diagnosis of chronic myeloproliferative neoplasms

      Gorana Gašljević
      (SI)

      9:20-9:40

      Atherosclerosis in
      MPN patients

      Ajda Anžič
      Drofenik (SI)

      9:40-9:45

      Discussion

       

       

       

       

      9:45-10:15

      Coffee/tea break

      UMC

       

       

       

      10:15-12:15

      WG2 Session: Hereditary Erythrocytosis and
      Thrombocytosis

      Co-chairs: Mary Frances Mc Mullin (UK),
      Celeste Bento (PT)

      10:15-10:35

      Molecular landscape
      of Hereditary Erythrocytosis and Thrombocytosis

      Mary Frances McMullin (UK)

      10:35-10:55

      Diagnostic
      algorithms for Hereditary Erythrocytosis

      Holger Cario
      (DE)

      10:55-11:15

      Diagnostic algorithm
      for erythrocytosis and
      retrospective analysis: a Slovenian experience

      Saša Anžej Doma (SI)
      / Irena Preložnik Zupan
      (SI)

      11:15-11:35

      Hemochromatosis and Hereditary Erythrocytosis

      Mark
      Catherwood (UK)

      11:35-11:45

      Novel Mutations in Iron Overload and Idiopathic Erythrocytosis

      Mathilde Filser
      (FR)

      11:45-11:55

      Short lecture

       

      11:55-12:05

      Short lecture

       

      12:05-12:15

      Discussion

       

       

       

       

      12:15-13:00

      General business session with coffee/tea

      Co-chairs: Sylvie Hermouet
      (FR), François Girodon (FR),
      Vladan
      Cokic (RS)

       

       

       

      13:00-14:30

      Lunch and free time
      for poster session and networking

      UMC

       

       

       

      14:30-16:15

      WG1 Session: Mutation detection, validation
      and quantification & MRD in MPN

      Co-chairs: Julia Asp (SE),

      Beatriz Bellosillo Paricio (ES)

      14:30-14:50

      Tba

      Tba

      14:50-15:10

      Tba

      Tba

      15:10-15:30

      Mutation detection
      in MPN: a Slovenian experience

      Helena Podgornik
      (SI)

      15:30-15:40

      Parallel algorithm
      for molecular genetic testing and haplotype 46/1 test in improves the
      “JAK2 tree” for MPN suspected patients

      Igor Olkhovskiy (RU)

      15:40-15:50

      Genetic prothrombotic risk factors in patients with Ph(-) myeloproliferative
      neoplasms

      Ivana Horvat (HR)

      15:50-16:00

      CALR mutations in a
      cohort of JAK2-negative patients with suspected MPN

      Tanja Belčič
      Mikič (SI)

      16:00-16:10

      Short lecture

       

      16:10-16:15

      Discussion

       

       

       

       

      16:15-16:45

      Coffee/tea break

      UMC

       

       

       

      16:45-18:15

      Special Session III: Oxygen sensing

      Co-chairs: Tanja Kunej (SI)

      16:45-17:05

      HIFA paralogs in
      cell response to hypoxia

      Tanja Kunej (SI)

      17:05-17:25

      Clinical consequences
      of erythrocytosis

      Mary Frances McMullin (UK)

      17:25-17:45

      Von Hippel Lindau
      Disease from clinician’s perspective

      Mojca Urbančič
      (SI)

      17:45-17:55

      Short lecture

       

      17:55-18:05

      Short lecture

       

      18:05-18:15

      Discussion

       

       

       

       

      20:00

      Conference Dinner

      Nebotičnik/Skyscraper, Ljubljana

       

       

       

      FRIDAY

      April 24th, 2020

       

      8:45-10:30

      Special Session IV: NGS in Hereditary
      Erythrocytosis

      Co-chairs: François Girodon
      (FR),

      Nataša Debeljak (SI)

      8:45-9:15

      The transformative
      impact of NGS in diagnosis and research of rare diseases

      Aleš Maver
      (SI)

      9:15-9:35

      NGS analysis in HE:
      a Portuguese experience

      Celeste Bento (PT)

      9:35-9:55

      NGS analysis in HE:
      a French experience

      François Girodon (FR)

      9:55-10:15

      NGS analysis in HE:
      a Slovenian experience

      Nataša Debeljak (SI)

      10:15-10:25

      Short lecture

       

      10:25-10:30

      Discussion

       

       

       

       

      10:30-11:00

      Coffee/tea break

      UMC

       

       

       

      11:00-13:00

      WG3 Session: Inflammation in
      MPNs

      Chair: Vladan Cokić (RS)

      11:00-12:00

      Role of inflammation
      in MPN disease initiation

      Radek Skoda (CH)

      12:00-12:20

      The pro-inflammatory
      and anti-inflammatory equilibrium in MPNs

      Vladan Cokic (RS)

      12:20-12:50

      Glucolipids, autoimmunity and inflammation in
      MPNs

      Sylvie Hermouet (FR)

      12:50-13:00

      Discussion

       

       

       

       

      13:00-14:00

      Lunch

      UMC

       

       

       

      14:00-15:00

       

      Visit of Ljubljana /
      Laboratories at University Medical Centre Ljubljana and Faculty of Medicine
      University of Ljubljana

      UMC & MF UL

       

       

       

      15:00

      Meeting Adjourns

       

       

       

      Participants

      Name Affiliation Country
      Vladan Cokic Institute for Medical Research, University of Belgrade Serbia
      Sylvie HERMOUET CRCINA Inserm U1232 France
      Nataša Debeljak Institute of Biochemistry, Faculty of Medicine, University of Ljubljana Slovenia
      Diklić Miloš Institute for Medical Research Serbia
      Aleša Kristan University of Ljubljana, Faculty of Medicine Slovenia
      Sandra Oloketuyi Laboratory of Environmental and Life Sciences, University of Nova Gorica, Slovenia Slovenia
      François GIRODON LABORATOIRE HEMATOLOGIE, CHU DIJON France
      Ivana Horvat Clinical department of laboratory diagnostics, University Hospital Center Zagreb Croatia
      Francesca Palandri S.Orsola-Malpighi University Hospital, Institute of Hematology “L. and A. Seràgnoli” Italy
      Radek Skoda Department of Biomedicine, University Hospital Basel Switzerland
      Konstanze Döhner Department of Internal Medicine III, University Hospital of Ulm Germany
      Dorota Link-Lenczowska Hematology and Genetic Diagnostic Department, The University Hospital in Krakow Poland
      Magdalena Zawada Hematology and Genetic Diagnostics Department, The University Hospital in Krakow Poland
      Mathilde Filser Laboratoire d’Hématologie CHU Dijon France
      Ana Livun Department for molecular biology and genetics, University hospital Dubrava Croatia
      Sandra Ropret Institute of Biochemistry, Universuty of Ljubljana, Faculty of Medicine Slovenia
      Mary Frances McMullin Centre for Medical Education, Queen’s University, Belfast, N. Ireland UK
      Gasljevic Gorana Department of Pathology, Institute of Oncology, Ljubljana Slovenia
      Ajda ANŽIČ Drofenik MD, Cardiology, Ljubljana Slovenia
      Igor Olkhovskiy Krasnoyarsk branch, Federal State budgetary Institution Hematology Research Center Department of Health RF
      Mojca Urbančič Department of Ophthalmology, University Medical Centre Ljubljana Slovenia
      Tanja Kunej Department of Animal Science, University of Ljubljana Slovenia
      Tanja Belčič Mikič Department of Haematology, University Medical Center Ljubljana Slovenia
      Ales Maver Clinical institute for Genomic Medicine, University medical centre Ljubljana Slovenia
      Alicja Bartoszewska-Kubiak Department of Clinical Genetics, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz Poland
      Alja Zottel Medical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana Slovenia
      Špela Stangler Herodež Laboratory for Medical genetics, UKC Maribor Slovenia
      Eva Drnovšek student of medicine, Ljubljana Slovenia
      Helena Podgornik Department of Hematology, UMC Ljubljana Slovenia
      Alenka Erjavec Škerget Laboratory of medical genetics, University medical Centre Maribor Slovenia
      Matjaz Sever Hematology, UMC Ljubljana Slovenia

      Organization

      Scientific committee

      Sylvie Hermouet
      François Girodon
      Vladan Čokić
      Julia Asp
      Beatriz Bellosillo Paricio
      Mary Frances Mc Mullin
      Celeste Bento
      Nataša Debeljak
      Irena Preložnik Zupan

      Organising committee

      Nataša Debeljak
      Irena Preložnik Zupan
      Polona Novak
      Matjaž Sever
      Saša Anžej Doma
      Helena Podgornik
      Tadeja Režen
      Petra Hudler
      Aleša Kristan
      Sandra Ropret
      Dubravka Germ
      Milena Božičnik
      Vladan Čokić

      Information

      Conference location

      The meeting will take place in the main building at University Medical Centre (UMC) Ljubljana.

      UNIVERSITY MEDICAL CENTRE LJUBLJANA
      Main building UMCL, Zaloška cesta 2, Slovenia
      1000 Ljubljana
      Web site: https://www.kclj.si/
      Map: https://www.kclj.si/index.php?dir=/pacienti_in_obiskovalci/stavbe_ukcl

      How to get there?

      You can travel to Ljubljana by air, train, bus or car. Visit how-to-reach-LJUBLJANA
      You can reach University Medical Centre Ljubljana (UMCL)  by bus or car.

      Bus station “Klinični center” is the closest station to the main building, where buses 2, 9, 11, 20 and 25 make their stops. For more information, see the webpage of LJUBLJANA PUBLIC TRANSPORT (http://www.lpp.si/en/public-transport).

      If you prefer travelling by car, using the parking garages may ease your search for a parking space. The closest garages are PG Šentpeter (Address: Njegoševa 8, 1000 Ljubljana) and PG Meksiko (Address: Zaloška cesta 1, 1000 Ljubljana).

      Contact with the organizers: Before contacting the organizers, please read carefully all information provided on the website. Questions may be asked through the Contact webpage. Thank you for your understanding and co-operation.

      How to register, submit a contribution, pay registration fees, get invoice? For registration, submission of contribution … select Registration on the menu bar.

      How to book accommodation? See Accommodation section below.

      Accommodation

      Each participant has to make his/her own room reservation.

      Recommended hotels:

      Hotel Lev, UNION HOTELS (https://www.uhcollection.si/)
      Vošnjakova ulica 1, Ljubljana,
      Distance: 1800 meters (about 25 min walking) from hotel to UMC Ljubljana.
      Special price for meeting attendants for Premier Double room with breakfast:
      Single use – 84 EUR/night
      Double use– 94 EUR/night
      The above prices include buffet-style breakfast, VAT, complimentary use of the hotel swimming pool, gym, and sauna at U Hotel, as well as Wi-Fi internet access inside the rooms. The prices exclude the city tax in the amount of € 3.13 / night / person.
      Link for reservation: https://reservations.travelclick.com/86073?groupID=2668580
      Last day for reservation: 25th March 2020
      After this date rooms will be available on request, please contact reservations department directly:
      lev@uhcollection.si or +386 1 308 1438

      B&B Hotel Ljubljana Park (www.hotelpark.si)
      Bleiweisova cesta 30, 1000 Ljubljana,
      Distance: 800 meters (about 10 min walking) from hotel to UMC Ljubljana.
      Special price for meeting attendants for Superior room with breakfast:
      Single use –95 EUR/night
      Double use – 110 EUR/night
      The prices exclude the city tax in the amount of € 3.13 / night / person.
      Email for reservation:
      Email to sales-ljubljana@hotelbb.com (Ms. Tonja Ronjić, +386 1 300 2529), stating that you are booking the room for “15th MPN&MPNr – EuroNet Meeting”.
      Last day for reservation: 21st March 2020

       

      Grand Hotel Union, UNION HOTELS (https://www.uhcollection.si/)
      Miklošičeva 1, Ljubljana,
      Distance: 1200 meters (about 15 min walking) from hotel to UMC Ljubljana.
      Special price for meeting attendants for Comfort Double room with breakfast:
      Single use – 112 EUR/night
      Double use– 122 EUR/night
      The above prices include buffet-style breakfast, VAT, complimentary use of the hotel
      swimming pool, gym, and sauna at U Hotel, as well as Wi-Fi internet access inside the
      rooms. The prices exclude the city tax in the amount of € 3.13 / night / person. We also
      offer a garage located at U Hotel, where you can park your car. The overnight parking is
      20 Eur.
      Link for reservation: https://reservations.travelclick.com/76847?groupID=2739973
      Last day for reservation: 1st April 2020
      After this date rooms will be available on request, please contact reservations
      department directly grand@uhcollection.si or +386 1 308 1989

      Ljubljana - Touristic information

      For touristic information you can visit Ljubljana Tourism webpage (https://www.visitljubljana.com/en/visitors/).

      Currency
      The Slovenian currency is the Euro (€).

      How to reach Ljubljana?
      You can travel to Ljubljana by air, train, bus or car. Visit how-to-reach-Ljubljana webpage
      (https://www.visitljubljana.com/en/visitors/travel-information/how-to-reach-ljubljana/).

      Essentials
      For more essential information visit essentials webpage (https://www.visitljubljana.com/en/visitors/travel-information/essentials/).

      Registration

      COVID-19 Update

      Due to the Covid-19 epidemy, we have to postpone the Ljubljana meeting to the period between September – November. New meeting dates, programme and registration deadline will be known by the end of May. Please do follow our homepage for more information.

      MPN&MPNr Ljubljana organising committee

       

      How to register?

      Deadline for abstract submission: March 2nd, 2020
      Early Bird Registration Deadline: March 16th, 2020

      Registration fees: 250 € until until March 16th, 2020 (included); 400 € for late registration.
      Registration fees include access to the conference, proceedings, lunches, gala dinner and coffee breaks.

      Payment instruction – For a wire transfer, state your name as payment reference.

      Attendance: Day1 (April 22nd ), Day 2 (April 23rd ), Day 3 (April 24th )

      Data Use Agreement
      By registering for this meeting, you (the delegate) agree that your personal data will be processed for registration and handling purposes only, as well as to send you information in connection with the symposium via e-mail. Any personal data will be solely used in accordance with current EU data protection legislation (GDPR) and will not be disclosed to a third party without the delegate written consent. If you will submit an abstract for this symposium it will be published on the symposium internet site and in the book of abstracts. If you do not submit the data indicated as we cannot complete your registration.

      Even if you are MPNrEuronet member or were a registered participant for a previous meeting or training school, you must restart the whole registration process, and click on REGISTRATION , fill the personal data form and submit it, verify the registered information.

      How to modify my data, submit and/or load an abstract?

      Once registered to this fifteenth meeting, you may come back at any time to your registration form by LOGIN with your last name and password, in order to:
      ⦁ modify any personal information for registration,
      ⦁ submit an abstract,
      ⦁ load your abstract file.

      The deadline for submission of abstracts is March 2nd, 2020.

      Photo

      Search

      Organization committee:

      Danijela Leković, Andrija Bogdanović, Nataša Debeljak and Vladan Čokić
      Medical faculty, University of Belgrade
      Institute for medical research, University of Belgrade
      Belgrade, Serbia

      Local organizers

      Faculty of Medicine University of Ljubljana

      University Medical Centre Ljubljana

      Slovenian Medical Association

      Slovenian Haematological Society

      Golden sponsor of MPN&MPNR-EURONET 16TH MEETING

      Former EU-sponsored COST Action BM0902 (2009-2013), a network of experts … “

      by MPN&MPNr-EuroNet.

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