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    • Home
    • Diagnostics
      • Polycythemia Vera
      • Essential Thrombocythemia
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      • Congenital Erythrocytosis
      • Hereditary Thrombocytosis
    • Molecular analyses
      • JAK2V617F
      • JAK2 Exon 12 mutations
      • Mpl/TPO_Receptor
      • Calreticulin (CALR)
      • Other genes mutated in MPN
      • EPO-Receptor
      • Oxygen sensing pathway genes
      • THPO
    • Events
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    • INTRANET

      La Baule April 2011

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      • La Baule April 2011

      Third MPN&MPNr-EuroNet Meeting

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      Aims

      The aims of MPN&MPNr-EuroNet’s third workshop being held in La Baule, France – April 6-8, 2011 are:

      1. to improve knowledge on the histopathology of MPN which do not carry mutations of JAK2. To do so, the meeting will begin on April 6th, 2011 with a plenary session, where invited speakers will describe the histopathology of MPN, with specific emphasis on MPL-mutated MPN.
      2. to inform participants on the newest developments in MPN and related congenital diseases.
      3. to exchange and diffuse information on the molecular assays developed for diagnosis or research in laboratories across Europe. To do so, abstracts will be selected for short talks in each of the working group sessions and posters will be presented during the whole length of the meeting. The short talks and the poster sessions are dedicated to sharing information on the various molecular assays used and the results obtained by participants to the meeting.
      4. to discuss and plan for the different tasks and objectives of the 4 working groups (WG). To do so, each WG will convene on April 7th, 2011 in plenary sessions under the direction of the WG chairs. New participants are encouraged to become actively involved in specific WG tasks.

      Objectives

      Thus, participants to the third MPN&MPNr-EuroNet meeting will have the opportunity to hear from the best experts about the newest developments in the molecular diagnosis of MPN and related congenital diseases. They will have the opportunity to present their own work and original diagnostic assays, and exchange with colleagues on the newest genes and techniques of interest in the field of MPN, congenital erythrocytosis and hereditary thrombocythemia. By joining one of MPN&MPNr-EuroNet working groups, they will be able to contribute actively, productively and durably in innovation, optimization and standardization of the biological diagnosis of MPN and related congenital diseases in Europe.

      Keywords

      molecular diagnosis, myeloproliferative neoplasms, congenital erythrocytosis, hereditary thrombocythemia, standardization, European network

      More info

      Click on the following link to get more info about MPN&MPNr-EuroNet.

      Abstract Submission

      Participants are encouraged to submit an abstract in relation to the diagnosis of MPN, congenital erythrocytosis, hereditary thrombocythemia, and the histopathology of MPN. Abstracts will be put together in an Abstract Book that will be distributed to participants during the meeting.

      Abstracts should be composed as follows:

      • Title
      • Names of co-authors
      • Institutions and addresses
      • E-mail address of corresponding author
      • Text (body of text less than 2000 characters, including spaces).

      Body of text: less than 2500 characters including spaces; should include Background, Aim(s), Methods, Results, Conclusion.

      The deadline for submission of abstracts is February 28th, 2011.
      In order to submit an abstract, participants should first be registered, then, being logged in, choose Abstract in the menu bar on Registration page.

      Scholarships

      MPN&MPN-EuroNet offers scholarships to early state researchers (ESR). ESR are biologists or clinicians who received their MD or PhD degree less than 10 years ago. To apply for a scholarship, ESR must submit an abstract (on line) and send a letter of motivation and their curriculum vitae to Mrs. Elodie Hervio . Click on the following link to send a mail to Mrs. Elodie Hervio.

      The deadline for application to a scholarship is February 28th, 2011.
      Applicants will be informed of the decision regarding attribution of scholarship via E-mail between March 1st and March 5th, 2011.

      Reimbursements of scholarship recipients

      Reimbursements of COST members and scholarship recipients COST Action BM 0902 Management Committee members, substitute members and scholarship recipients must register in e-COST in order to be reimbursed for their travel and lodging expanses. Click on the following link to get access to e-COST. To allow sufficient time for treating the files of all individuals applying for reimbursement, we highly recommend registration in e-COST before March 15th, 2011.

      Programme

      Third MPN&MPNr-EuroNet Meeting

      WEDNESDAY APRIL 6th, 2011

      16:00 – 17:00 Welcome and registration
      17:00 – 19:00 Histopathology of MPN – Chair: Jiri Schwarz Prague, Czechia
      17:00 – 17:40 The links between molecular biology and histopathology
      in BCR/ABL-negative MPNs
      Kais Hussein Hannover, Germany
      17:40 – 18:00 Our experience with the WHO 2008 classification
      for the diagnosis of MPN using bone marrow biopsies
      Juraj Marcinek Martin, Slovakia
      18:00 – 18:20 Distinction between JAK2V617F-mutated ET
      and pre-polycythemic PV: gray zone or reality?
      Vit Campr Prague, Czechia
      18:20 – 18:40 Studies of MPL mutations in ET: survey of the literature Paola Guglielmelli Florence, Italy
      18:40 – 19:00 General discussion
      19:00 – 19:15 MPN&MPNr-EuroNet’s First Training School: “Detection of mutations in MPN: theory, practice (qPCR, HRM)”
      Nîmes, May 11-13, 2011
      Serge Carillo Nîmes, France
      19:15 – 20:00 Refreshments & Manned Poster Session

      THURSDAY APRIL 7th, 2011

      08:00 – 10:30 WG 1: JAK2-mutated MPN – Chair: Niels Pallisgaard Veijle, Denmark
      08:00 – 08:15 Tracing the impact of the JAK2V617F mutation: A case report Jana Markova Prague, Czechia
      08:15 – 08:30 CD133+/JAK2V617F+ cells from peripheral blood of PMF patients differentiate in hematopoietic and endothelial progenitors in vitro Ioanna Triviai Hamburg, Germany
      08:30 – 08:45 The ELN comparative study of JAK2V617F assays Niels Pallisgaard Vejle, Denmark
      08:45 – 09:00 Reference materials Sylvie Hermouet Nantes, France
      09:00 – 09:30 Pre-analysis: what material should be used for diagnosis and MRD? Niels Pallisgaard Vejle, Denmark
      09:30 – 10:00 The “low JAK2V617F burden” study Eric Lippert Bordeaux, France
      10:00 – 10:20 MRD calculations algorithms and QC issues Niels Pallisgaard Vejle, Denmark
      10:20 – 10:30 Subgroup drafting JAK2V617F guidelines
      Collection of rare JAK2 mutations: Case stories, reference materials
      Niels Pallisgaard Vejle, Denmark
      10:30 – 11:00 Coffee break & Poster session
      11:00 – 12:30 WG 3: Congenital Erythrocytosis – Chair: Mary Frances McMullin Belfast, United Kingdom
      11:00 – 11:30 Erythropoietin and its receptor: A tale beyond erythropoiesis Drorit Neumann Tel Aviv, Israel
      11:30 – 11:45 Gene expression analysis of erythropoiesis-associated genes Kais Hussein Hannover, Germany
      11:45 – 12:00 Report from HypoxiaNet Davos meeting: Oxygen 2011 Mary Frances McMullin Belfast, UK
      Sylvie Hermouet Nantes, France
      12:00 – 12:15 Update on WG3 website pages Kais Hussein Hannover, Germany
      12:15 – 12:30 MPN&MPNr-EuroNet’s Second Training School:
      “Congenital Erythrocytoses” Coimbra, Portugal, October 2011
      Miscellaneous
      Celeste Bento Coimbra, Portugal

      Mary Frances McMullin Belfast, UK

      12:30 – 14:00 Lunch & Poster session
      14:00 – 16:30 WG 2: MPN without JAK2 mutation – Chair: Jiri Schwarz Prague, Czechia
      14:00 – 14:15 In BCR-ABL1 negative MPN the detection of JAK2exon12, MPLW515, CBL, KITD816V, FIP1L1-PDGFRA mutations are closely linked to specific entities, whereas the JAK2V617F, TET2, or EZH2 mutations demonstrate a broader diversity: Patterns from diagnostic reports of 18,547 patients analyzed Susanne Schnittger Münich, Germany
      14:15 – 14:30 Expression of wild type Mpl and Jak2 is linked, frequently low in MPN, and Jak2V617F contributes to counter low Mpl levels Mathias Vilaine Nantes, France
      14:30 – 15:00 The histopathological study of ET and PMF with MPL mutation: Organization of the study Jiri Schwarz Prague, Czechia
      15:00 – 15:30 MPL mutation detection: Results of the first quality control Stéphane Giraudier Créteil, France
      Naomi Porret Bern, Switzerland
      15:30 – 15:45 Reference materials Sylvie Hermouet Nantes, France
      15:45 – 16:30 Update on WG2 website pages
      Hereditary Thrombocytosis subgroup
      Jiri Schwarz Prague, Czechia
      16:30 – 17:00 Coffee break & Poster session
      17:00 – 19:00 WG 4: Scientific cooperation, communication – Chair: to be announced
      17:00 – 17:30 2011 fall meeting Susanne Schnittger Münich, Germany
      17:30 – 17:45 Recruitment of new members François Girodon Dijon, France
      17:45 – 18:15 Website to be announced
      18:15 – 18:45 Intranet (Forum) to be announced
      18:45 – 19:00 Research grants Sylvie Hermouet Nantes, France
      20:00 – 22:00 Gala Dinner

      FRIDAY APRIL 8th, 2011

      09:00 – 12:00 Management Committee Meeting – Chairs: Sylvie Hermouet, Eric Lippert France
      09:00 – 10:30 2011 budget & Other administrative items
      Scientific issues (I)
      Sylvie Hermouet Nantes, France
      10:30 – 11:00 Coffee break & Poster session
      11:00 – 12:00 Scientific issues (II)
      Questions, Suggestions & Discussion
      Eric Lippert Pessac, France
      Sylvie Hermouet Nantes, France
      12:00 – 14:00 Lunch
      14:00 Adjourn

      Participants

      Information

      Conference location

      Palais des Congrès, Atlantia
      119, avenue du Maréchal de Lattre de Tassigny
      44500 La Baule – France
      Tél : +33 (0)2 40 11 51 51

      Contact with the organizers

      Before to contact the organizers, please read carefully the information provided on the web site. Questions may ONLY be asked through the contact webpage.

      How to register, submit a contribution, pay registration fees, get invoice ?

      For registration, submission of contribution … select Registration on the menu bar.

      How to get there?

      By air …

      The closest airport is Nantes Airport flights and schedules here, that offers regular connexion with more than 60 french, european and international cities and capitals, and 5 flights per day to/from Paris CDG.
      From Nantes Airport, you may use the shuttle(6,20 euros ; Shuttle timing) or a taxi (25 à 35 €) to get in Nantes train station and there take a train to La Baule (see below).
      You may also share a taxi with other paticipants, that will take you directly to La Baule (about 1hr drive).
      Last, if enough people are interested, MPN&MPNr-EuroNet can arrange for a shuttle bus from the Nantes airport to La Baule. If you are interested, please click on the following link to send a mail to Mrs. Elodie Hervio, stating your interest in a Nantes-La Baule shuttle and the day and time of arrival of your flight.

      By train…

      • TGV Europe information
      • From Paris (Gare Montparnasse) to La Baule, you will have at least one TGV departure per hour, and the train trip will take 2h50.
      • From Nantes train station, get here TGV and train shedule.

      By car …

      • Google Map
      • Consult Mappy or Viamichelin or use your GPS N 47° 28′ W -2° 40′ or program your navigator:
        119, avenue du Maréchal de Lattre de Tassigny, 44500 LA BAULE
      • … from Paris: expressway A11, 450 km – 4h30
      • … from Nantes: speedway, 45 mn
      • … from Rennes: 1h30

      Accommodation

      Each participant has to make his/her own room reservation.

      One possibility is to book through the website of Tourist Office of La Baule.
      Click Here, enter the following code in uppercase and without space: MPN2011 and make your choice. Please be patient as the booking pages are very slow to uplaod.

      La Baule - Touristic information

      • La baule here, and here.
      • Loire Atlantique

      Photo

      Search

      Organization committee:

      Danijela Leković, Andrija Bogdanović, Nataša Debeljak and Vladan Čokić
      Medical faculty, University of Belgrade
      Institute for medical research, University of Belgrade
      Belgrade, Serbia

      Supported by

      about Cost

      about European Science Foundation

      Former EU-sponsored COST Action BM0902 (2009-2013), a network of experts … “

      by MPN&MPNr-EuroNet.

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