Third MPN&MPNr-EuroNet Meeting
Aims
The aims of MPN&MPNr-EuroNet’s third workshop being held in La Baule, France – April 6-8, 2011 are:
- to improve knowledge on the histopathology of MPN which do not carry mutations of JAK2. To do so, the meeting will begin on April 6th, 2011 with a plenary session, where invited speakers will describe the histopathology of MPN, with specific emphasis on MPL-mutated MPN.
- to inform participants on the newest developments in MPN and related congenital diseases.
- to exchange and diffuse information on the molecular assays developed for diagnosis or research in laboratories across Europe. To do so, abstracts will be selected for short talks in each of the working group sessions and posters will be presented during the whole length of the meeting. The short talks and the poster sessions are dedicated to sharing information on the various molecular assays used and the results obtained by participants to the meeting.
- to discuss and plan for the different tasks and objectives of the 4 working groups (WG). To do so, each WG will convene on April 7th, 2011 in plenary sessions under the direction of the WG chairs. New participants are encouraged to become actively involved in specific WG tasks.
Objectives
Thus, participants to the third MPN&MPNr-EuroNet meeting will have the opportunity to hear from the best experts about the newest developments in the molecular diagnosis of MPN and related congenital diseases. They will have the opportunity to present their own work and original diagnostic assays, and exchange with colleagues on the newest genes and techniques of interest in the field of MPN, congenital erythrocytosis and hereditary thrombocythemia. By joining one of MPN&MPNr-EuroNet working groups, they will be able to contribute actively, productively and durably in innovation, optimization and standardization of the biological diagnosis of MPN and related congenital diseases in Europe.
Keywords
molecular diagnosis, myeloproliferative neoplasms, congenital erythrocytosis, hereditary thrombocythemia, standardization, European network
More info
Click on the following link to get more info about MPN&MPNr-EuroNet.
Abstract Submission
Participants are encouraged to submit an abstract in relation to the diagnosis of MPN, congenital erythrocytosis, hereditary thrombocythemia, and the histopathology of MPN. Abstracts will be put together in an Abstract Book that will be distributed to participants during the meeting.
Abstracts should be composed as follows:
- Title
- Names of co-authors
- Institutions and addresses
- E-mail address of corresponding author
- Text (body of text less than 2000 characters, including spaces).
Body of text: less than 2500 characters including spaces; should include Background, Aim(s), Methods, Results, Conclusion.
The deadline for submission of abstracts is February 28th, 2011.
In order to submit an abstract, participants should first be registered, then, being logged in, choose Abstract in the menu bar on Registration page.
Scholarships
MPN&MPN-EuroNet offers scholarships to early state researchers (ESR). ESR are biologists or clinicians who received their MD or PhD degree less than 10 years ago. To apply for a scholarship, ESR must submit an abstract (on line) and send a letter of motivation and their curriculum vitae to Mrs. Elodie Hervio . Click on the following link to send a mail to Mrs. Elodie Hervio.
The deadline for application to a scholarship is February 28th, 2011.
Applicants will be informed of the decision regarding attribution of scholarship via E-mail between March 1st and March 5th, 2011.
Reimbursements of scholarship recipients
Reimbursements of COST members and scholarship recipients COST Action BM 0902 Management Committee members, substitute members and scholarship recipients must register in e-COST in order to be reimbursed for their travel and lodging expanses. Click on the following link to get access to e-COST. To allow sufficient time for treating the files of all individuals applying for reimbursement, we highly recommend registration in e-COST before March 15th, 2011.
Third MPN&MPNr-EuroNet Meeting
WEDNESDAY APRIL 6th, 2011 |
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| 16:00 – 17:00 | Welcome and registration | |
| 17:00 – 19:00 | Histopathology of MPN – Chair: Jiri Schwarz Prague, Czechia | |
| 17:00 – 17:40 | The links between molecular biology and histopathology in BCR/ABL-negative MPNs |
Kais Hussein Hannover, Germany |
| 17:40 – 18:00 | Our experience with the WHO 2008 classification for the diagnosis of MPN using bone marrow biopsies |
Juraj Marcinek Martin, Slovakia |
| 18:00 – 18:20 | Distinction between JAK2V617F-mutated ET and pre-polycythemic PV: gray zone or reality? |
Vit Campr Prague, Czechia |
| 18:20 – 18:40 | Studies of MPL mutations in ET: survey of the literature | Paola Guglielmelli Florence, Italy |
| 18:40 – 19:00 | General discussion | |
| 19:00 – 19:15 | MPN&MPNr-EuroNet’s First Training School: “Detection of mutations in MPN: theory, practice (qPCR, HRM)” Nîmes, May 11-13, 2011 |
Serge Carillo Nîmes, France |
| 19:15 – 20:00 | Refreshments & Manned Poster Session | |
THURSDAY APRIL 7th, 2011 |
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| 08:00 – 10:30 | WG 1: JAK2-mutated MPN – Chair: Niels Pallisgaard Veijle, Denmark | |
| 08:00 – 08:15 | Tracing the impact of the JAK2V617F mutation: A case report | Jana Markova Prague, Czechia |
| 08:15 – 08:30 | CD133+/JAK2V617F+ cells from peripheral blood of PMF patients differentiate in hematopoietic and endothelial progenitors in vitro | Ioanna Triviai Hamburg, Germany |
| 08:30 – 08:45 | The ELN comparative study of JAK2V617F assays | Niels Pallisgaard Vejle, Denmark |
| 08:45 – 09:00 | Reference materials | Sylvie Hermouet Nantes, France |
| 09:00 – 09:30 | Pre-analysis: what material should be used for diagnosis and MRD? | Niels Pallisgaard Vejle, Denmark |
| 09:30 – 10:00 | The “low JAK2V617F burden” study | Eric Lippert Bordeaux, France |
| 10:00 – 10:20 | MRD calculations algorithms and QC issues | Niels Pallisgaard Vejle, Denmark |
| 10:20 – 10:30 | Subgroup drafting JAK2V617F guidelines Collection of rare JAK2 mutations: Case stories, reference materials |
Niels Pallisgaard Vejle, Denmark |
| 10:30 – 11:00 | Coffee break & Poster session | |
| 11:00 – 12:30 | WG 3: Congenital Erythrocytosis – Chair: Mary Frances McMullin Belfast, United Kingdom | |
| 11:00 – 11:30 | Erythropoietin and its receptor: A tale beyond erythropoiesis | Drorit Neumann Tel Aviv, Israel |
| 11:30 – 11:45 | Gene expression analysis of erythropoiesis-associated genes | Kais Hussein Hannover, Germany |
| 11:45 – 12:00 | Report from HypoxiaNet Davos meeting: Oxygen 2011 | Mary Frances McMullin Belfast, UK Sylvie Hermouet Nantes, France |
| 12:00 – 12:15 | Update on WG3 website pages | Kais Hussein Hannover, Germany |
| 12:15 – 12:30 | MPN&MPNr-EuroNet’s Second Training School: “Congenital Erythrocytoses” Coimbra, Portugal, October 2011 Miscellaneous |
Celeste Bento Coimbra, Portugal
Mary Frances McMullin Belfast, UK |
| 12:30 – 14:00 | Lunch & Poster session | |
| 14:00 – 16:30 | WG 2: MPN without JAK2 mutation – Chair: Jiri Schwarz Prague, Czechia | |
| 14:00 – 14:15 | In BCR-ABL1 negative MPN the detection of JAK2exon12, MPLW515, CBL, KITD816V, FIP1L1-PDGFRA mutations are closely linked to specific entities, whereas the JAK2V617F, TET2, or EZH2 mutations demonstrate a broader diversity: Patterns from diagnostic reports of 18,547 patients analyzed | Susanne Schnittger Münich, Germany |
| 14:15 – 14:30 | Expression of wild type Mpl and Jak2 is linked, frequently low in MPN, and Jak2V617F contributes to counter low Mpl levels | Mathias Vilaine Nantes, France |
| 14:30 – 15:00 | The histopathological study of ET and PMF with MPL mutation: Organization of the study | Jiri Schwarz Prague, Czechia |
| 15:00 – 15:30 | MPL mutation detection: Results of the first quality control | Stéphane Giraudier Créteil, France Naomi Porret Bern, Switzerland |
| 15:30 – 15:45 | Reference materials | Sylvie Hermouet Nantes, France |
| 15:45 – 16:30 | Update on WG2 website pages Hereditary Thrombocytosis subgroup |
Jiri Schwarz Prague, Czechia |
| 16:30 – 17:00 | Coffee break & Poster session | |
| 17:00 – 19:00 | WG 4: Scientific cooperation, communication – Chair: to be announced | |
| 17:00 – 17:30 | 2011 fall meeting | Susanne Schnittger Münich, Germany |
| 17:30 – 17:45 | Recruitment of new members | François Girodon Dijon, France |
| 17:45 – 18:15 | Website | to be announced |
| 18:15 – 18:45 | Intranet (Forum) | to be announced |
| 18:45 – 19:00 | Research grants | Sylvie Hermouet Nantes, France |
| 20:00 – 22:00 | Gala Dinner | |
FRIDAY APRIL 8th, 2011 |
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| 09:00 – 12:00 | Management Committee Meeting – Chairs: Sylvie Hermouet, Eric Lippert France | |
| 09:00 – 10:30 | 2011 budget & Other administrative items Scientific issues (I) |
Sylvie Hermouet Nantes, France |
| 10:30 – 11:00 | Coffee break & Poster session | |
| 11:00 – 12:00 | Scientific issues (II) Questions, Suggestions & Discussion |
Eric Lippert Pessac, France Sylvie Hermouet Nantes, France |
| 12:00 – 14:00 | Lunch | |
| 14:00 | Adjourn | |
Conference location

Palais des Congrès, Atlantia
119, avenue du Maréchal de Lattre de Tassigny
44500 La Baule – France
Tél : +33 (0)2 40 11 51 51
Contact with the organizers
Before to contact the organizers, please read carefully the information provided on the web site. Questions may ONLY be asked through the contact webpage.
How to register, submit a contribution, pay registration fees, get invoice ?
For registration, submission of contribution … select Registration on the menu bar.
How to get there?
By air …
The closest airport is Nantes Airport flights and schedules here, that offers regular connexion with more than 60 french, european and international cities and capitals, and 5 flights per day to/from Paris CDG.
From Nantes Airport, you may use the shuttle(6,20 euros ; Shuttle timing) or a taxi (25 à 35 €) to get in Nantes train station and there take a train to La Baule (see below).
You may also share a taxi with other paticipants, that will take you directly to La Baule (about 1hr drive).
Last, if enough people are interested, MPN&MPNr-EuroNet can arrange for a shuttle bus from the Nantes airport to La Baule. If you are interested, please click on the following link to send a mail to Mrs. Elodie Hervio, stating your interest in a Nantes-La Baule shuttle and the day and time of arrival of your flight.
By train…
- TGV Europe information
- From Paris (Gare Montparnasse) to La Baule, you will have at least one TGV departure per hour, and the train trip will take 2h50.
- From Nantes train station, get here TGV and train shedule.
By car …
- Google Map
- Consult Mappy or Viamichelin or use your GPS N 47° 28′ W -2° 40′ or program your navigator:
119, avenue du Maréchal de Lattre de Tassigny, 44500 LA BAULE - … from Paris: expressway A11, 450 km – 4h30
- … from Nantes: speedway, 45 mn
- … from Rennes: 1h30
Accommodation
Each participant has to make his/her own room reservation.
One possibility is to book through the website of Tourist Office of La Baule.
Click Here, enter the following code in uppercase and without space: MPN2011 and make your choice. Please be patient as the booking pages are very slow to uplaod.
La Baule - Touristic information
- La baule here, and here.
- Loire Atlantique

