Sixth MPN&MPNr-EuroNet Workshop
Aims
The aims of MPN&MPNr-EuroNet’s sixth workshop to be held in Billund, Denmark, on October 24-26, 2012 are:
- to share information on the newest developments in MPN and related congenital diseases, congenital erythrocytosis and hereditary thrombocythemia;
- to exchange and diffuse information on the molecular assays developed for diagnosis or research in laboratories working on MPN and related diseases across Europe;
- to discuss and plan for the various tasks and objectives of the 4 working groups (WG).
To do so, abstracts will be selected for short talks in each of the working group sessions and posters will be presented during the whole length of the meeting.
Each WG will convene under the direction of the WG chairs, first on October 24th and 25th, 2012 in plenary sessions, then in simultaneous study groups, on October 25th and 26th, 2012. New participants are encouraged to become actively involved in specific WG tasks. In addition, plenary sessions will cover the newest knowledge in MPN, with special focus on genetics, epigenetics, and hypoxia response pathways.
Objectives
Participants to the sixth MPN&MPNr-EuroNet meeting will have the opportunity to hear from the best experts about the newest developments in the molecular diagnosis of MPN and related congenital diseases. They will have the opportunity to present their own work and original diagnostic assays, and exchange with colleagues on the newest genes and techniques of interest in the field of MPN, congenital erythrocytosis and hereditary thrombocythemia. By joining one of MPN&MPNr-EuroNet working groups, they will be able to contribute actively, productively and durably in innovation, optimization and standardization of the biological diagnosis of MPN and related congenital diseases in Europe.
Keywords
molecular diagnosis, myeloproliferative neoplasms, congenital erythrocytosis, hereditary thrombocythemia, standardization, European network
More info
Click on the following link to get more info about MPN&MPNr-EuroNet.
Abstract Submission
Participants are encouraged to submit an abstract in relation to the diagnosis of MPN, new mutations in MPN, the histopathology of MPN, inflammation in MPN, congenital erythrocytosis, hereditary thrombocythemia, and the JAK/STAT STAT and other signalling pathways of interest in MPN. Early stage researchers and junior biologists and clinicians are especially encouraged to submit abstracts.
Abstracts should be composed as follows:
- Title
- Names of co-authors
- Institutions and addresses
- E-mail address of corresponding author
- Text (body of text less than 2000 characters, including spaces).
All abstracts will be put together in an Abstract Book that will be distributed to participants during the meeting.
The deadline for submission of abstracts is September 7th, 2012.
In order to submit an abstract, participants should first be registered, then, being logged in, choose Abstract in the menu bar on Registration page.
Scholarships
MPN&MPN-EuroNet offers scholarships to early state researchers (ESRs). ESRs are PhD students, researchers, biologists or clinicians who received their MD or PhD degree less than 8 years ago. To apply for a scholarship, ESRs must submit an abstract following the on line procedure, and send a letter of motivation and their curriculum vitae to Mrs. Elodie Hervio. Click on the following link to send a mail to Mrs. Elodie Hervio.
The deadline for application to a scholarship is September 7th, 2012.
Applicants will be informed of the decision regarding attribution of scholarship via E-mail between September 17th and September 21st, 2012.
Reimbursements of scholarship recipients
Reimbursements of COST members and scholarship recipients
COST Action BM 0902 Management Committee members, substitute members and scholarship recipients must register in e-COST in order to be reimbursed for their travel and lodging expanses. Click on the following link to get access to e-COST. To allow sufficient time for treating the files of all individuals applying for reimbursement, registration in e-COST should be done before September 30th, 2012.
Sixth MPN&MPNr-EuroNet Workshop
WEDNESDAY 24 October, 2012 |
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| 09:00 – 12:30 | Pre-meeting : Special Working Group on Patient Databank (limited to 10) | Celeste Bento, PT |
| 12:30 – 14:00 | Lunch | |
| 16:00 – 16:30 | Welcome and Registration | Niels Pallisgaard, DK |
| 16:30 – 18:35 | Symposium : Inflammation in MPN part I – Chair: Hans Hasselbalch, DK | |
| 16:30 – 17:00 | Chronic inflammation and MPN | Hans Hasselbalch, DK |
| 17:00 – 17:30 | Discovery and development of JAK inhibitors for the treatment of myeloproliferative neoplasms | Thomas Radimerski, CH |
| 17:30 – 17:50 | The clinical role of JAK inhibitors in MPN | Hans Hasselbalch, DK |
| 17:50 – 18:00 | Incyte Corp JAK2V617F allelic burden assay | Timothy Burn, USA |
| 18:00 – 18:15 | Donor chimerism versus JAK2 V617F quantification post-allogeneic haematopoietic stem cell transplantation: a pilot evaluation from the Irish Adult Bone Marrow Transplantation Centre | K. Haslam, IE |
| 18:15 – 18:30 | Should paroxysmal noctural haemoglobinuria be classified as a chronic myeloproliferative neoplasm ? | S. Langabeer, IE |
| 18:30 – 18:45 | Information on 2012 and 2013 Training Schools | Serge Carillo, FR Beatriz Bellosillo, ES |
| 19:00 – 20:30 | Buffet dinner & Poster Session | |
THURSDAY 25 October, 2012 |
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| 09:00 – 11:00 | Symposium : Inflammation in MPN part II – Chair: Sylvie Hermouet, FR | |
| 09:00 – 09:30 | Links between Inflammation and Hypoxia | Comac Taylor, IE |
| 09:30 – 10:00 | Inflammation-linked cytokines in MPN | Sylvie Hermouet, FR |
| 10:00 – 10:30 | HSP-90 in MPN | François Girodon,FR |
| 10:30 – 10:45 | Chimeras between Epidermal Growth Factor and Erythropoietin Receptors (EGFR-EPOR) for Exploring Function of Erythrocytosis-Driving Mutations in the EPO-R Cytosolic Domain | M. Gross, IL |
| 10:45 – 11:00 | Distinct deregulation of the hypoxia inducible factor (HIF) by germline PHD2 mutants identified in patients presenting with congenital erythrocytosis | B. Gardie, FR |
| 11:00 – 11:30 | Coffee break & Posters | |
| 11:30 – 13:00 | WG 1: JAK2-mutated MPN – Chair: Niels Pallisgaard, DK | |
| 11:30 – 11:40 | Low burden JAK2V617F study | Eric Lippert, FR |
| 11:40 – 11:50 | Danish Low burden JAK2V617F study | Cecilie Rank, DK Hans Hasselbalch, DK |
| 11:50 – 12:00 | Update on rare JAK2 mutations | Serge Carillo, FR |
| 12:00 – 12:15 | JAK2 exon 12 Study | Lasse Kjaer, DK |
| 12:15 – 12:30 | Reference material | Niels Pallisgaard, DK |
| 12:30 – 12:45 | Interlaboratory Quality Control study (IQ-control Study) | Niels Pallisgaard, DK |
| 12:45 – 13:00 | Bead-based liquid assay for detection of JAK2 EXON 12 mutations | V. Shivarov, BG |
| 13:00 – 13:15 | Group Photograph | |
| 13:15 – 14:00 | Lunch & Posters | |
| 13:30 – 15:00 | Management Committee Meeting | |
| 15:00 – 15:30 | Coffee break & Posters | |
| 15:30 – 17:30 | WG 3: Congenital Erythrocytosis – Chair: Mary Frances McMullin, UK | |
| 15:30 – 16:15 | Gene variant databases; current demands and possibilities | Johan den Dunnen, NL |
| 16:15 – 16:45 | Clinical Database | Holger Cario, DE |
| 16:45 – 17:00 | High affinity Haemoglobins | Melanie Percy, UK |
| 17:00 – 17:15 | Histology Study of erythrocytosis | Mary Frances McMullin UK on behalf of Bridget Wilkins UK |
| 17:15 – 17:30 | Molecular heterogeneity of mutations in patients with familial erythrocytosis | J. Kucerova, CZ |
| 17:30 – 18:00 | Break & Posters | |
| 18:00 – 19:00 | WG 4: Scientific cooperation, communication – Chair: Lars Palmqvist, SE | |
| 18:00 – 18:10 | Upcoming meeting – April 24-26, 2013: Ohrid, Republic of Macedonia | Irina Panovska-Stavridis, MK |
| 18:10 – 18:20 | Upcoming meeting – September 25-27 2013: Prague, The Czech Republic | Jiri Schwarz, Prague, CZ |
| 18:20 – 18:45 | Update on recruitment of new member countries – Website and Intranet Forum – Other issues | François Girodon, FR Lars Palmqvist, SE Mathias Vilaine, FR |
| 18:45 – 19:00 | MPN&MPNr-EuroNet beyond 2013, Research grants | Sylvie Hermouet, FR |
| 19:30 – 22:30 | Gala Dinner | |
FRIDAY 26 October, 2012 |
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| 09:00 – 10:30 | WG 2: MPN without JAK2 mutation – Chair: Jiri Schwarz, CZ | |
| 09:00 – 09:20 | Workflow of molecular investigations in JAK2-negative MPNs The Munich experience |
Susanne Schnittger, DE |
| 09:20 – 09:40 | Workflow of molecular investigations in JAK2-negative MPNs The Barcelona experience |
Beatriz Bellosillo, ES |
| 09:40 – 10:00 | Molecular investigations in Ph- MPDs -diagnostic and classification needs. The Czech view | Jiri Schwarz, CZ |
| 10:00 – 10:15 | Interlaboratory MPL Quality Control study | Naomi Porret, CH |
| 10:15 – 10:30 | MPL mutational analysis using a competitive allele-specific Taqman assay | L. Martinez Aviles, ES |
| 10:30 – 11:00 | Coffee break | |
| 11:00 – 11:45 | Simultaneous Business Meetings WG1 : JAK2-mutated MPN WG3 : Congenital Erythrocytosis |
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| 11:45 – 12:30 | Simultaneous Business Meetings WG2: MPN without JAK2 mutation WG4: Scientific cooperation, communication |
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| 12:30 – 13:30 | Lunch | |
51 registered participants on 07-12-2019
| # | Name | Affiliation | Country |
|---|---|---|---|
| 1 | Sylvie Hermouet | Inserm UMR892/CNRS UMR6299 | France |
| 2 | François Girodon | CHU Dijon | France |
| 3 | Mary Frances McMullin | Queens University Belfast | UK |
| 4 | Melanie Percy | Belfast City Hospital | N. Ireland |
| 5 | Drorit Neumann | Tel-Aviv University | Israel |
| 6 | Veronique Laloux | IPSOGEN SA | France |
| 7 | Dina Naguib | CHU Cote de Nacre | France |
| 8 | Stephen Langabeer | St. James’s Hospital | Ireland |
| 9 | Betty Gardie | Ecole Pratique des Hautes Etudes | France |
| 10 | Eric Lippert | CHU de Bordeaux | France |
| 11 | Maj Westman | Copenhagen University Hospital | Denmark |
| 12 | Miguel Vieira da Silva | Senso Comum | Portugal |
| 13 | Celeste Bento | Hospital Pediatrico Coimbra | Portugal |
| 14 | Luz Martinezaviles | Hospital del Mar | Spain |
| 15 | Velizar Shivarov | National Hematology Hospital | Bulgaria |
| 16 | Thomas Radimerski | Novartis Institutes for BioMedical Research | Switzerland |
| 17 | Holger Cario | University Medical Center Ulm | Germany |
| 18 | Jana Kucerova | Palacky University Olomouc | Czech Republic |
| 19 | Karl Haslam | St. James’s Hospital | Ireland |
| 20 | Irina Panovska-Stavridis | University Clinic of Hematology-Skopje | Rep of Macedonia |
| 21 | Naomi A. Porret | Inselspital Bern and University of Berne | Switzerland |
| 22 | Serge Carillo | CHU CAREMEAU | France |
| 23 | Ã…sa Nilsson | Genanalys | Sweden |
| 24 | Carolina Simonson | Genanalys | Sweden |
| 25 | Hans Hasselbalch | Roskilde Hospital, University of Copenhagen | Denmark |
| 26 | Cecilie Frank | Roskilde Hospital, University of Copenhagen | Denmark |
| 27 | Maruska Marusic | Dubrava University Hospital | Croatia |
| 28 | Lasse Kjaer | Herlev Hospital | Denmark |
| 29 | Hajnalka Andrikovics | Hungarian National Blood Transfusion Service | Hungary |
| 30 | Marieta Costache | University of Bucharest | Romania |
| 31 | Zuzana Zidova | Faculty of Medicine and Dentistry, Palacky Univer | Czech Republic |
| 32 | Morten Andersen | Copenhagen University Hospital, Rigshospitalet | Denmark |
| 33 | Timothy Burn | Incyte Corp | USA |
| 34 | Beatriz Bellosillo | Hospital del Mar | Spain |
| 35 | Selcuk Sozer Tokdemir | Isstanbul University | Turkey |
| 36 | Jana Marková | Institute of Hematology and Blood Transfusion | Czech Republic |
| 37 | Rikke Fredslund Andersen | Vejle Hospital | Denmark |
| 38 | Maurus Locher | Genetica AG | Switzerland |
| 39 | Niels Pallisgaard | Vejle Hospital | Denmark |
| 40 | Fabian Chablais | Genetica AG | Switzerland |
| 41 | Stylianos Ventis | BioAnalytica GenoType S.A. | Greece |
| 42 | Evangelos Alexiadis | BioAnalytica-GenoType SA | Greece |
| 43 | Elisabeth Oppliger Leibundgut | University Hospital Bern | Switzerland |
| 44 | Susanne Schnittger | MLL Munich Leukema laboratory | Germany |
| 45 | Mor Gross | Tel Aviv university | Israel |
| 46 | Johannes Den Dunnen | LUMC | The Netherlands |
| 47 | Cormac Taylor | UCD Conway Institute | Ireland |
| 48 | Jiri Schwarz | Institute of Hematology and Blood Transfusion | Czechia |
| 49 | Tine Hougaard | Novartis | Denmark |
| 50 | Annette Schmitt-Graeff | Institut of Pathology | Germany |
| 51 | Maria Åström | Department of Medicine | Sweden |
Conference location
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| LEGOLAND® Hotel & Conference Booking and Conference Service Aastvej 10, DK-7190 Billund, Denmark Phone : +45 75 33 12 44 – Fax : +45 75 35 38 10 Hotel LEGOLAND® is a 4-star conference hotel in Billund, situated just 3 km from Denmark’s second largest airport, Billund Airport For booking your room please see below in Accommodation section.. |
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Contact with the organizers: Before to contact the organizers, please read carefully all information provided on the web site. Questions may ONLY be asked through the Contact webpage. Thank you for your understanding and co-operation.
How to register, submit a contribution, pay registration fees, get invoice ? For registration, submission of contribution … select Registration on the menu bar.
How to get there?
Travelling to Billund by air …
The closest airport is Billund Airport A/S, located 5 min (3 km) from Legoland conference center (2nd largest airport in Denmark). The airport has direct flights to most of Europe and the rest of the world.
Transfer to the hotel from the airport takes 5 min taxi journey.
Travelling to Billund by car …
The Google coordinates for the hotel are 55.733654, 9.127756 and for the airport 55.745823,9.147856 The hotel is close to the main motorway network.
- From the south: Take the A7/ E45 to Junction 63 (Bramdrupdam), then the 441 towards Bredsten and the 28 to Billund or the 176 via Egtved.
- From the north: Take the E45 to Junction 57 (Horsens S) and follow signs to Billund.
- From Funen: Take the E20 north in the direction of Vejle/ Århus to Junction 61 (Vejle S), then the 18 towards Vejle and the 28 to Billund.
Free parking tickets for the meeting will be available via the internet (links will be provided by the hotel).
Travelling to Billund by train …
It is also possible but inconvenient to take the train to the nearest railway station Vejle and from there, bus services virtually drive you to and from the door (approx. 30 km/30 min).
Maps
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Google Map of LEGOLAND® Hotel & Conference. |
Accommodation
Each participant has to make his/her own room reservation.
It is recommended to stay at Hotel Legoland (connected to the conference centre).
All meals are included in the conference price, starting Wednesday afternoon with coffee and ending Friday with lunch.
A pre-booked block of 75 rooms is available at a special price of DKK 900 per night (Euro 120) including breakfast (normal price is Euro 200), accompanying person DKK 200 per night (including breakfast).
For booking your room, please send a mail to hotel@legoland.dk and mention the discount code 18422 to benefit from our special rate. Payment for the hotel at your departure.





